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Make an enquiry and we will help you calculate the total price to buy Nexletol (bempedoic acid) online and have it delivered where you live. Our Patient Support Team will personally assist you along the way, Nexletol (bempedoic acid) is an adenosine triphosphate-citrate lyase (ACL) inhibitor indicated for the treatment of hypercholesterolemia (high blood cholesterol levels) with:1, Nexletol (bempedoic acid) is taken as an addition (adjunct) to diet and highest tolerated statin therapy.1, It is available in capsule form containing 180 mg bempedoic acid.1, Bempedoic acid is a medicine that lowers low-density lipoprotein (LDL) cholesterol (known as ‘bad’ cholesterol). When paying by credit card, you can pay online once you have received your order confirmation. They will be there to support and guide you in anyway possible to help you get the medicine you need. Next we will also verify that you have a prescription from a doctor in your home country for the medicine you need. References: 1. Generally, our Named Patient support fee, shipping costs and any local tax (if applicable) are not included in the product price that is displayed on our website … Bempedoic acid, also known as ESP-55016 and ETC-1002, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. The lowest GoodRx price for the most common version of Nexletol is around $333.12, … Bempedoic acid is a first-in-class oral … JavaScript seems to be disabled in your browser. IMPORTANT NOTICE ABOUT IMPERSONATION SCAMS: Unauthorized individuals or entities are impersonating ESPERION colleagues through spoofed email, text messages and social media in an effort to gain access to bank account information and/or other personal information. Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom) The FDA approved the Esperion drug, bempedoic acid (Nexletol), late Friday. Fill out this form to enquire about Nexletol (bempedoic acid). Creating a password allows you to receive a quote and approve it or reject it in your dashboard. Evaluation of major cardiovascular events in patients with, or at high risk for, cardiovascular disease who are statin intolerant treated with bempedoic acid (ETC-1002) or placebo (CLEAR Outcomes). Price 2.5 Bempedoic acid and bempedoic acid–ezetimibe costs £55.44 per 28-pack, excluding VAT. The best thing would be to check with your country's own health ministry. We will never share your number with 3rd parties. Cold symptoms such as stuffy nose, sneezing, sore throat. Nexletol (bempedoic acid) is a medication for the treatment of hypercholesterolemia (high blood cholesterol levels). Such requests are fraud schemes and are not … In most cases we will respond to you via email, however for more complex situations, a call ensures we can process your request faster. The most common side effects include hyperuricemia (high blood levels of uric acid), pain in arms or legs, and anemia (low red blood cell counts).. Bempedoic acid blocks an … It contains 180 mg of bempedoic acid. Clinical Trial CLEAR Wisdom (NCT02991118), cited on Nov 5, 2020, 3. Aysen Simsek and her team offered assistance during a very difficult time. With a targeted mechanism of action, bempedoic acid is a first-in-class, complementary, orally available, once-daily ATP Citrate Lyase (ACL) inhibitor that, reduces cholesterol biosynthesis and lowers LDL-C by up-regulating the LDL receptor. In some countries we might also need an import license. Total Value. (USD/kg) $1,573. It works by reducing the amount of cholesterol made by the liver. (kg) 5,007 kg. Make an enquiry below to learn more. Bempedoic acid is a prodrug and requires activation by the enzyme very-long-chain acyl-CoA synthetase 1, which is present in the liver but absent in most peripheral tissues. For the best experience on our site, be sure to turn on Javascript in your browser. Please be aware that due to the COVID-19 situation worldwide and the country lockdowns, we will sometimes experience delays in shipping and shortages in availability. We support you to access approved medicine that is not approved or available in your country of residence. The shipping fee might also include the cost of special packaging, such as coolboxes, cool packs and data loggers, as well as transport insurance to guarantee that you receive your medicine in good order. For lowering cholesterol, NEXLETOL is often taken with other medicines, including a group of medicines called statins. heterozygous familial hypercholesterolemia, established atherosclerotic cardiovascular disease. When you buy Nexletol (bempedoic acid), you can make the payment by bank transfer or by credit card. Lowering "bad" cholesterol may help to decrease the risk of heart disease and help prevent strokes and heart attacks. The most common side effects (≥20% of patients) listed in the prescribing information include:1, The serious adverse reactions listed in the prescribing information include:1, Nexletol (bempedoic acid) can cause fetal harm when administered to a pregnant woman, it is advised to avoid pregnancies and breastfeeding.1, For a comprehensive list of side effects and adverse reactions please refer to the official prescribing information.1, 1. Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol (CLEAR Harmony) Some countries have a government fund providing financial assistance for citizens to access lifesaving medical treatment abroad. Bempedoic acid, sold under the brand name Nexletol among others, is a medication for the treatment of hypercholesterolemia (high blood cholesterol levels).. Always consult your treating physician before starting a course of treatment. We will walk you through the specific import regulations that are required for your shipping destination. Esperion Announces Agreement with Otsuka Pharmaceutical Co., Ltd. for Development and Commercialization of NEXLETOL™ (bempedoic acid) and NEXLIZET™ (bempedoic acid and ezetimibe) Tablets in Japan This means that a consistent room temperature of 15 to 25°C is maintained during transit. If you have a question about its approval in a specific country feel free to contact our support team. Conclusions: Bempedoic acid may be cost-effective within the Australian healthcare setting at an annual acquisition price less than $600. The difference between bempedoic acid and placebo in mean percent change in LDL-C from baseline to Week 12 was -17% [95% CI: -21, -14].4, Please refer to the summary of product characteristics below and in the resource section for comprehensive information about the safety and effectiveness of Nexletol (bempedoic acid) for the approved indication.5, 1. Total Quantity. Bempedoic acid and ezetimibe is used together with a low-fat diet and other medicines to lower LDL cholesterol in adults with an inherited form of high cholesterol . Please be aware that a 2.8% fee applies when paying by credit card. Data on file. Bempedoic acid is a novel adjunct lipid-lowering therapy in cardiovascular disease. Your order will be shipped to you by our partner couriers, such as DHL, UPS and specialised cold chain couriers. As a result, bempedoic acid lowers blood levels of cholesterol, including LDL-cholesterol and other fatty substances made by the liver.1,2, Statins lower cholesterol by blocking the activity of another cholesterol-forming enzyme, named HMG-CoA reductase. Bempedoic acid and ezetimibe is a combination medicine that is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL). The Named Patient support fee is tiered relative to the cost of the medicine. We operate solely under the TheSocialMedwork brand name. You can read a detailed overview of prices and costs here. Press release, Feb 21, 2020, The Food and Drugs Administration (FDA) approval of Nexletol (bempedoic acid) for the treatment of adults with high cholesterol who are receiving guideline-recommended statin therapy was based on the data of studies CLEAR Harmony (NCT02666664) and CLEAR Wisdom (NCT02991118).1,2, CLEAR Harmony was a multi-center, randomized, double-blind trial that studied the safety of bempedoic acid in patients with hypercholesterolemia. 2. You can also pick up your medicine from our partner pharmacy in Amsterdam or our partner pharmacy in Luxembourg after the order has been paid for. Number of Transactions. We do not have any partnership with distributors, agents or any other entities. Bempedoic Acid. Full prescribing information [FDA]: Nexletol (bempedoic acid), Esperion Announces FDA Approval of NEXLETOL™ (bempedoic acid) Tablet, an Oral, Once-Daily, Non-Statin LDL-Cholesterol Lowering Medicine, Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony), Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk (CLEAR Wisdom), Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol, Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease. After you have accepted our offer, our experienced logistics team will arrange all the shipping and transportation of your medicine. Nexletol (bempedoic acid) was approved by: Nexletol is the first oral, once-daily, non-statin LDL-C lowering medicine approved since 2002 for indicated patients.3. It might be possible for you to claim the cost of Nexletol (bempedoic acid) via your country's healthcare system. Hamstrung by payer pushback, Repatha and Praluent have been engaged in a long-running price war aimed at courting access as well as undercutting each other. How and where to buy Nexletol: You can order Nexletol from TheSocialMedwork if the drug has not been approved or is not available in your country. Bempedoic acid is used along with a proper diet and other medications to help lower "bad" cholesterol (such as LDL) in the blood. Please note that this medicine may have also been approved in other regions than the ones we’ve listed. We will work hard to keep you informed at every step along the way and get your medicine to you quickly and safely. Once we have verified your prescription and medical details, our expert sourcing team will work with our global network of suppliers to find you the best price. Generally, our Named Patient support fee, shipping costs and any local tax (if applicable) are not included in the product price that is displayed on our website unless stated otherwise. Once we have found you the lowest possible cost for your medicine, we will present you with a final offer for your approval. Similarly, 100 patients in both the BAþEZE FDC and bempedoic acid groups would provide 98% or greater power to detect a slightly … Following an FDA approval Friday, Esperion intends to sell bempedoic acid under the brand name Nexletol for a price of about $10 per day. You'll find more details highlighted below. • CLEAR Harmony demonstrated bempedoic acid reduces low-density lipoprotein. If you choose "Other", we will let you know when we have created a guide for your country. 3 Committee discussion The appraisal committee considered evidence submitted by Daiichi Sankyo, a review of this submission by the evidence review group (ERG), the technical report, and Bempedoic acid also can be used with another class of heart drugs, called PCSK9 inhibitors, which are injectable medications launched in 2015. AB - Background: Bempedoic acid is a novel adenosine triphosphate (ATP) citrate lyase inhibitor shown to reduce low density lipoprotein cholesterol (LDL-C) when used as an adjunct lipidlowering … To date, we have assisted patients in over 80 countries to access thousands of life-improving medicines. We will price the way that branded oral LDL cholesterol drugs have traditionally been priced, that is around $9 to $10 a day, or around $3500 wholesale acquisition cost. Full prescribing information [FDA]: Nexletol (bempedoic acid) [PDF] Something is missing. They are reliable, honest, punctual and do everything to meet your needs…”, “Dr. 6, 9, 10 In the CLEAR Harmony trial (n = 2230), bempedoic acid reduced LDL-C levels by 18% at 12 weeks. 9 Similarly, the CLEAR WISDOM trial (n = 779) presented at the 2019 American College of Cardiology (ACC) meeting, … Should you be in doubt, please contact us by email. Collected information will not be shared with any third party and complies with our stated Privacy Policy. The cost for a monthly or yearly treatment of Nexletol (bempedoic acid) depends on your prescription requirements which includes the dosage in mg and medicine type (Capsules). Clinical Trial CLEAR Harmony (NCT02666664), cited on Nov 5, 2020, 2. Nexletol Prices. 11 - 50. Esperion is also awaiting an FDA decision on its bempedoic acid-ezetimibe combo, which is currently under regulatory review and scored a win in a phase 2 trial in August. Nilemdo (bempedoic acid) "Accessible is also important – for PCSK9 inhibitors, the challenge isn't … • The Markov model simulated the clinical outcomes and costs over a lifetime. Make an enquiry for more information. TheSocialMedwork provides access to Nexletol (bempedoic acid) on the Named Patient import basis, which means that we work on behalf of the patient in cooperation with their treating doctor. Goldberg AC, JAMA, Nov 12, 2019, 5. Nexletol (bempedoic acid) price and additional costs The price of Nexletol (bempedoic acid) The base cost of each medicine is set by the manufacturer. The price, packaging size and strength may vary due to product availability. Since we help patients access medicines not available in their home country, our first step is to check that the medicine you need is not currently available in your home country. Esperion, Feb 21, 2020. Esperion, based in Ann Arbor, Mich., announced results from its Phase III Study 2 of bempedoic acid at the American College of Cardiology (ACC) annual meeting. The price of the medicines you see on sale is the cost set by the manufacturer. Metrochem API Pvt Ltd is a Bempedoic acid API manufacturer in india.We are having technically the maximum superior manufacturing centers and our complete production procedure is as per regulatory policies.We are based on meeting our client’s needs.This helps us to produce innovative quality goods at an competitive price … Esperion, Feb 21, 2020, 2. For bempedoic to be an effective alternative to PCSK9 inhibitors will likely come to price, said Ballantyne. Nexletol (bempedoic acid) is a member of the miscellaneous antihyperlipidemic agents drug class and is commonly used for High Cholesterol - Familial Heterozygous. • Generally, we do not support medical insurance, but we do provide you with an invoice after you make the payment that you may send to your medical insurance company so they can reimburse you. It is a means of raising funds by using an online platform to group together many small donations from friends, family and others, in order to help you afford medical treatment. NEXLETOL is a tablet that you take by mouth. Pain in your back, shoulder, legs, or arms. – Study 1 Demonstrated Bempedoic Acid Significantly Lowered LDL-Cholesterol and Reduced hsCRP – – Over 52-Weeks, Bempedoic Acid was Observed to be Safe, Well-Tolerated, and Did Not Lead to Higher Overall Adverse Events Compared With Placebo – – Bempedoic Acid is an Oral, Once-daily ATP Citrate Lyase (ACL) Inhibitor that Reduces Cholesterol and Fatty Acid … The drug is being developed as a complementary, cost-effective, once-daily, oral cholesterol-lowering therapy. The shipping cost depends on the medicine and the destination country. You will receive an email with a download link to your guide (or a confirmation if you selected Other) at [email protected]. Though bempedoic acid does not lower LDL-C nearly as much as the PCSK9 inhibitors, its appeal may lie in a lower expected price and oral administration. Our Patient Support team will guide you throughout the process. I was in a very difficult situation with a tight schedule, and their amazing team members…”. Skip to the beginning of the images gallery, 100% success delivering to people in 85 countries, By clicking "Download guide", you agree to receive emails from TheSocialMedwork (including the TheSocialMedwork newsletter and announcements). Crowdfunding might also be an option for you. You can pay by bank transfer or credit card. The first thing we need is a prescription from your treating physician. We are registered and audited by the Dutch Ministry of Health in The Hague as an Independent Intermediary for Medicines, registration number 6730 BEM and as a Pharmaceutical Distributor with the registration number 16258 G. We support the United Nation’s 2030 Sustainable Development Goals related to Health and Equality. Full prescribing information [FDA]: Nexletol (bempedoic acid) [PDF] The shipping fees may include the shipping from our supplier to our partner pharmacy as well as the shipping costs to deliver the medicine to the patient’s country of residence. Average Price. We believe that it is important that they are affordable," said Mayleben. Can I take NEXLETOL with other medicines? Please check your spam or junk folder. We organise the sourcing, shipment and safe delivery of your medicine. Collected information will not be shared with any third party and complies with our stated. Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. E sperion, the maker of bempedoic acid, said they plan to price the drug, assuming it’s cleared for market, cheaper than the PCSK9 inhibitors and are currently seeking approval for the agent as a standalone … NEXLETOL (bempedoic acid) tablets, for oral use Initial U.S. Approval: 2020 -----INDICATIONS AND USAGE-----­ NEXLETOL is an adenosine triphosphate-citrate lyase (ACL) inhibitor indicated as an adjunct to diet … Medicine information contained herein may be time sensitive. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost. We also highly recommend checking out local patient blogs, communities and patient organisations to find out more about your options. Click on the “Make an enquiry” button to send us any questions you have or to upload your prescription if you already have one. Esperion Therapeutics, Inc. 2019. This reduces the development of atherosclerotic plaques that may increase the risk of cardiovascular events. The cost for Nexletol oral tablet 180 mg is around $354 for a supply of 30 tablets, depending on the pharmacy you visit. In addition, shipping costs and a Named Patient support fee will apply. To date we have successfully delivered packages to over 75 countries around the world. It does so by blocking adenosine triphosphate citrate lyase, which is an enzyme in the liver that is responsible for making cholesterol.

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